Tretinoin · Niacinamide
Most PrescribedTreat face wrinkles and fine lines for
$34.50 / month
Starting with a 2-month supply
Tretinoin · Niacinamide
Most PrescribedTreat face wrinkles and fine lines for $34.50 / month
Starting with a 2-month supply
Prescription-strength tretinoin, dermatology's most-studied anti-aging active. It smooths fine lines, refines texture, evens tone, and keeps breakouts in check, while niacinamide, Centella asiatica, and ceramides keep your barrier calm through treatment.
Treats the following anti-aging concerns:
Active ingredients:
Active ingredients:
Active ingredients:
As with any prescription retinoid, some people notice mild, temporary effects as their skin adjusts to treatment. These are typically short-lived and manageable with simple care steps.
Common adjustment effects can include mild dryness, peeling, itching, or redness. Applying a moisturizer helps soothe irritation, and most people find their skin settles within the first few weeks. A board-certified dermatologist on our clinical team reviews your case and sets a formulation appropriate for your skin.
After cleansing, apply one pump to your fingertips and gently massage onto your face at night — or as directed by the dermatologist on your clinical team.
Follow with a gentle, hydrating moisturizer to keep your skin comfortable as it adjusts.
Wear a broad-spectrum sunscreen, minimum SPF 30, every morning. Tretinoin makes your skin more sensitive to sun, so daily protection isn’t optional.
The Precision Dark Spot Corrector
A prescription-strength spot treatment that targets isolated dark spots, sun spots, and stubborn discoloration.
The Redness Control Formula
A daytime prescription that visibly reduces facial redness and flushing.
Prescription-strength tretinoin, dermatology's most-studied anti-aging active. It smooths fine lines, refines texture, evens tone, and keeps breakouts in check, while niacinamide, Centella asiatica, and ceramides keep your barrier calm through treatment.
Treats the following anti-aging concerns:
Active ingredients:
Active ingredients:
Active ingredients:
As with any prescription retinoid, some people notice mild, temporary effects as their skin adjusts to treatment. These are typically short-lived and manageable with simple care steps.
Common adjustment effects can include mild dryness, peeling, itching, or redness. Applying a moisturizer helps soothe irritation, and most people find their skin settles within the first few weeks. A board-certified dermatologist on our clinical team reviews your case and sets a formulation appropriate for your skin.
After cleansing, apply one pump to your fingertips and gently massage onto your face at night — or as directed by the dermatologist on your clinical team.
Follow with a gentle, hydrating moisturizer to keep your skin comfortable as it adjusts.
Wear a broad-spectrum sunscreen, minimum SPF 30, every morning. Tretinoin makes your skin more sensitive to sun, so daily protection isn’t optional.
The Precision Dark Spot Corrector
A prescription-strength spot treatment that targets isolated dark spots, sun spots, and stubborn discoloration.
The Redness Control Formula
A daytime prescription that visibly reduces facial redness and flushing.
The clinical team
The Anti-Aging SolutionRx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu — three board-certified dermatologists with combined decades of clinical experience treating women who want to start prescription anti-aging before the concerns get harder to address. Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.
What's in the bottle
The Anti-Aging Solution Rx pairs one prescription retinoid with three supporting ingredients designed to keep your barrier intact and your skin comfortable while the medication does its work. Four ingredients. One purpose. No marketing language wrapped around the names.
Active Ingredients
THE CORRECTOR
A prescription-strength retinoid — roughly 100× more potent than the strongest over-the-counter retinol. Accelerates cell turnover, smooths fine lines, evens tone, and builds collagen over time. The single most-studied anti-aging active in dermatology.
THE BUFFER
A form of vitamin B3 that reduces redness, evens tone, and supports your skin barrier. Makes the retinoid more tolerable from week one — and quietly improves the look of your skin on its own.Supporting Ingredients
THE CALMER
A clinically studied botanical that soothes irritation during the adjustment period. Used in dermatology for decades for its barrier-supporting properties. The reason your first weeks on tretinoin won't feel like a punishment.
THE BARRIER REPAIR
Lipids that reinforce the skin barrier and lock in moisture. Retinoid tolerance comes down to barrier health — ceramides keep yours strong enough to stay on treatment long enough to see results.Exact concentrations are determined by your dermatology provider based on your assessment, your tolerance, and your skin's history. Compounded medications are not FDA-approved.
What to expect
The Anti-Aging SolutionRx works while you sleep. Tretinoin accelerates cell turnover and builds collagen over time — the single mechanism behind both smoother texture and softer fine lines. Niacinamide evens tone and reduces redness, Centella asiatica soothes the adjustment period, and ceramides reinforce your barrier so the retinoid does its job without compromising your skin's comfort.
The Anti-Aging Solution Rx is a Core-tier prescription. That means it's strong enough to actually move the needle on fine lines, texture, and tone — and gentle enough to be your first prescription anti-aging treatment, not your last resort.
Starting to notice fine lines, early texture changes, dullness, or uneven tone
Tired of OTC retinols that promise prescription-strength results without the prescription
Wanting to stay ahead of aging before the concerns get harder to reverse
Ready for your first prescription anti-aging treatment — or stepping up from over-the-counter retinols that have stopped delivering
Able to tolerate a prescription retinoid, as confirmed during your assessment
Dealing with deeper wrinkles, loss of firmness, or visible photoaging — The Advanced Anti-Aging SolutionRx is built for higher-intensity cases
Pregnant, nursing, or trying to conceive — tretinoin isn't appropriate; your assessment will route you to a safer option
Primarily concerned about active acne — The Acne SolutionRx is built for that
Mostly dealing with persistent redness or rosacea flushing — The Redness Control FormulaRx is built for that
Already on isotretinoin (Accutane), or finished a course within the past 6 months — we'll need to space your treatment appropriately
I started noticing fine lines in my early 30s and wanted to do something about it before they got worse. DermClick got me on a real prescription fast. My skin looks smoother than it has in years.
Sarah M.
I had heard about tretinoin for years but always assumed I needed an in-office visit to get it. DermClick made it so easy. My skin tone is noticeably more even and my fine lines have visibly softened.
Claire B.
This is exactly what I was looking for: a dermatologist-designed prescription that actually works, without the long wait or the high cost. My skin feels and looks genuinely younger.
Natalie R.
Realistic timeline
Prescription retinoid treatment isn't a one-week fix. Real anti-aging results take time — but they're real, they hold, and they compound.
Here's what most people experience:
Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.
Weeks 1–2
Weeks 3–6
Weeks 7–12
Beyond 12 weeks
Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.
Three steps. No appointments. Reviewed by a board-certified dermatologist within one business day.
Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.
Your case is reviewed in 24 business hours, and your prescription is written by a licensed dermatology provider.
Tretinoin
NiacinamideYour formula is compounded by a licensed pharmacy and shipped to your door — usually within a week. Your dermatologist stays with you, adjusting your formula as your skin responds.
Because OTC retinols are roughly 1/100th the potency of prescription tretinoin — that's regulation, not marketing. If your over-the-counter retinol was going to smooth your fine lines and even your tone, it would have done it by now. Tretinoin is the same active your dermatologist would prescribe in-office, calibrated to your tolerance and supported with niacinamide, Centella asiatica, and ceramides so you can actually stay on it. The strength difference is the entire point.
The Anti-Aging Solutionᴿˣ is our first-line prescription anti-aging formula — built around tretinoin, ideal for people starting to notice fine lines, early texture changes, dullness, or uneven tone. The Advanced Anti-Aging Solutionᴿˣ is the maximum-strength tier — built around tazarotene, a next-generation retinoid, for deeper wrinkles, loss of firmness, and more visible photoaging. If you're not sure, take the assessment. A board-certified dermatologist on your care team will tell you which one matches where your skin actually is — not where you think it should be.
If you don't have active breakouts, you typically won't experience the breakout-style purge that acne patients see on tretinoin. What you may experience instead is a short adjustment period: mild dryness, peeling, or sensitivity as your skin gets used to the increased cell turnover. This usually lasts 2 to 6 weeks. The ceramides and Centella asiatica in the formula are included specifically to keep this phase manageable. If it gets uncomfortable, message us and we'll adjust your ramp-up or your formula.
Most of your routine can stay. Gentle cleansers, hydrating serums, broad-spectrum SPF (especially important on tretinoin), and barrier-supporting moisturizers all pair well with The Anti-Aging Solutionᴿˣ. What you should pause: other topical retinoids (additional tretinoin, adapalene, tazarotene, retinol), strong exfoliants like glycolic acid or salicylic acid at high concentrations, vitamin C serums at night (use them in the morning instead), and physical scrubs. A board-certified dermatologist on your care team will review your current products during your assessment and tell you exactly what to keep, what to drop, and what to add.
The assessment specifically asks. The Anti-Aging Solutionᴿˣ contains tretinoin, which is not safe during pregnancy or while nursing. If any of these apply to you, a board-certified dermatologist on your care team will route you to a safer alternative. If we can't safely prescribe for you, we'll tell you before charging you. We don't write prescriptions that shouldn't be written.
Most people start noticing a real shift between weeks 6 and 12 with consistent nightly use. Weeks 1–2 are the adjustment period. Weeks 3–6, your texture starts to smooth and your tone begins to even out. Weeks 6–12, fine lines look softer and your skin looks brighter overall. Beyond 12 weeks, the collagen-building work compounds over months and years. Tretinoin treatment is steady, not dramatic — but the results hold, and they're the closest thing in topical skincare to actually slowing the visible aging process.
Full prescribing details, including side effects, drug interactions, and who shouldn't use this treatment, are available on our Important Safety Information page. We recommend reading it before starting treatment.
The Anti-Aging Solution Rx is our first-line prescription anti-aging formula. If your concerns are more visible — deeper lines, loss of firmness, visible photoaging — there's a maximum-strength tier built for that.
Adapalene · Clindamycin · Niacinamide
$34.50/mo
Billed every 2 months. Cancel anytime. Skip or delay refills. Total per cycle: $69.00.
A daily prescription formula that helps keep pores clear and control acne-prone breakouts.
Treats:Acne · Clogged pores · Texture · Oiliness · Blackheads
Tazarotene · Niacinamide
$44.50/mo
Billed every 2 months. Cancel anytime. Skip or delay refills. Total per cycle: $89.00.
The most potent prescription retinoid — for skin that already tolerates a retinoid and wants faster results on lines, texture, and breakouts.
Targets:Deeper wrinkles · Texture · Breakouts · Pores · Photoaging
Tranexamic Acid · Kojic Acid · Tretinoin · Niacinamide
$35.50/mo
Billed every 2 months. Cancel anytime. Skip or delay refills. Total per cycle: $71.00.
A hydroquinone-free prescription formula that fades stubborn dark spots and uneven tone from multiple angles.
Targets:Stubborn dark spots · Uneven tone · Post-acne marks · Dullness