
Oxymetazoline
THE VASOCONSTRICTOR
A prescription active that works directly on the blood vessels behind facial redness, visibly reducing flushing within hours of application. The active that calms redness at its source.Rosacea · Daytime Control
Oxymetazoline · Niacinamide
Rosacea · Daytime Control
Oxymetazoline · Niacinamide
If your rosacea means your face is red at the meeting, in the photo, and at dinner — and you can't wait weeks for treatment to kick in — this is the prescription that works the same day you start.
Built with prescription oxymetazoline to visibly reduce redness and flushing within hours of application and niacinamide to support the barrier — with Centella asiatica soothing reactivity and ceramidesprotecting against the environmental triggers that worsen rosacea. A real prescription for visible daytime control — designed to layer with your ongoing rosacea treatment, not replace it.
Common concerns:
Designed by board-certified dermatologists. Prescribed by a board-certified dermatologist on our clinical team.
plan pricing
$34.50/mo
Billed every 2 months. Cancel anytime. Skip or delay refills.
Short assessment · Reviewed within one business day
The clinical team
The Redness Control Formula Rx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu — three board-certified dermatologists with decades of combined experience treating real patients.
Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.

What's in the bottle
The Redness Control Formula Rx pairs two prescription actives with two supporting ingredients — built for visible daytime relief, with the barrier protection that holds it.
Active Ingredients

THE VASOCONSTRICTOR
A prescription active that works directly on the blood vessels behind facial redness, visibly reducing flushing within hours of application. The active that calms redness at its source.
THE BARRIER SUPPORT
A form of vitamin B3 that strengthens the skin barrier and reduces the appearance of visible redness, supporting a calmer, more even complexion.Supporting Ingredients

THE CALMER
A clinically studied botanical that soothes irritation and supports recovery. Used in dermatology for decades — the quiet ingredient that keeps the strong ones comfortable.
THE BARRIER REPAIR
Lipids that reinforce the skin barrier and lock in moisture, protecting reactive skin against the environmental triggers — heat, sun, wind — that intensify rosacea.Exact concentrations are determined by a board-certified dermatologist on our care team based on your assessment, your tolerance, and your skin's history. Compounded medications are not FDA-approved.
What to expect

The Redness Control Formula Rx is designed around the visible appearance of redness — the symptom — while your ongoing rosacea formula supports the broader skin pattern.
Oxymetazoline works on the blood vessels in your skin to reduce flushing and visible redness within hours, with the effect lasting through most of the day — with niacinamide, Centella asiatica, and ceramides supporting the barrier and reducing reactivity to the environmental triggers (heat, sun, wind) that intensify rosacea.

The Redness Control Formula Rx is the rare prescription that works visibly in hours, not weeks. Oxymetazoline acts directly on blood vessels to reduce visible redness and flushing on the days you can't afford to look flared. It's designed to layer on top of your underlying rosacea treatment — not replace it. Think of it as daytime symptom control while your root-cause treatment does its slow work.
Noticing visible facial redness that shows up in every photo and meeting
Experiencing flushing or vascular redness that worsens with heat, sun, or stress
Looking for a daytime formula to layer with an ongoing rosacea treatment
Needing same-day visible relief for events, meetings, or photos
Prescription formula that may be continued through pregnancy — confirmed at assessment
Interested in targeted symptom control, as confirmed during your assessment
Have a history of cardiovascular disease, high blood pressure, or Raynaud's syndrome
Taking MAO inhibitors or have taken them in the past 14 days
Looking for one formula for rosacea-prone redness with papules and pustules — The Advanced Redness Solutionᴿˣ is built for that
Only experiencing inflammatory papules or pustules without visible redness — The Clarifying Rosacea Formulaᴿˣ or The Redness & Acne Formulaᴿˣ may be the better fit
I put it on the morning of my sister's wedding and the redness was visibly down before the photos. I've never had anything work that fast. Now it's part of my routine every single morning.
Nicole P.
My nightly formula is doing the slow work, but this is what gets me through the day. I apply it after cleansing, wait a bit, then makeup as usual. Meetings, photos, dinners — my face finally stays calm through all of it.
Amanda G.
I used to plan my week around how red my face was. Within an hour of applying, the flushing settles and holds through the afternoon. It sounds small, but not thinking about my skin all day is huge.
Tessa R.
Realistic timeline
Unlike most rosacea treatments, oxymetazoline works visibly the same day.
Here's what most patients experience.
Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

Day 1
Week 1
Weeks 2–4
Ongoing
Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.
Three steps. No appointments. Reviewed by a board-certified dermatologist within one business day.
Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.




Your case is reviewed within one business day, and your prescription is written by a board-certified dermatologist on our clinical team.

Your formula is compounded by a licensed pharmacy and shipped to your door — usually within a week. Your dermatologist stays with you, adjusting your formula as your skin responds.

It's the only one that works visibly the same day. The Redness & Acne Formulaᴿˣ, The Advanced Redness Solutionᴿˣ, and The Clarifying Rosacea Formulaᴿˣ are built for ongoing rosacea-prone skin concerns — including papules, pustules, and acne-like breakouts. They work on a timeline of weeks. The Redness Control Formulaᴿˣ uses oxymetazoline to visibly reduce redness through vasoconstriction — it is designed around the appearance of redness, not deeper flare support. Most patients use it alongside an ongoing rosacea formula.
Some patients do — particularly if their primary concern is visible flushing and vascular redness without significant papules, pustules, or breakouts. But for most rosacea-prone skin, the best results come from pairing The Redness Control Formulaᴿˣ with an ongoing formula selected for their broader skin pattern. A board-certified dermatologist on your care team will assess your case during the assessment and recommend whether to add another formula.
Most patients see visible redness reduction within 30 minutes to 3 hours of application. The peak effect typically lasts through most of the day. Some patients see fuller results across the first few days of use as they refine application amount and timing. Individual response varies — your DermClick care team can help you optimize your protocol if results aren't holding.
Yes — oxymetazoline is a vasoconstrictor, and there are important considerations. It's not recommended for patients with a history of cardiovascular disease, severe hypertension, Raynaud's syndrome, or for those taking MAO inhibitors. A board-certified dermatologist on your care team will review your medical history during your assessment to confirm this is safe for you. Read the full Important Safety Information before starting treatment.
Yes. Apply The Redness Control Formulaᴿˣ to clean, dry skin in the morning, wait 15 to 20 minutes for it to absorb fully, then apply your moisturizer, SPF, and makeup as usual. Many patients find the formula creates a smoother base for makeup application because the skin underneath is visibly calmer.
No. Oxymetazoline is not recommended during pregnancy or nursing. If you're pregnant, planning to be, or nursing, The Redness & Acne Formulaᴿˣ — built around azelaic acid — is the pregnancy-safe rosacea option in our lineup. If your pregnancy status changes during treatment, contact your DermClick care team immediately so your prescription can be adjusted.
The Redness Control Formula Rx is built for visible daytime relief. If you also need support for broader rosacea-prone skin concerns — papules, pustules, reactivity, or acne-like breakouts — these are the formulas that pair most naturally with it.