Acne · Core Formula

The Acne Solution^Rx

Name: The Acne Solution
Brand: DermClick
Price: 69.00 USD

Adapalene · Clindamycin Phosphate · Niacinamide

Clearer, calmer breakouts.

$34.50/month

Starting with a 2-month supply

Free shipping
Skip or delay refills
HSA/FSA eligible
Ongoing support

Treatment list

The Acne Solution ingredient texture callouts

The Acne Solution benefits for resistant and inflammatory breakouts

The Acne Solution best for mild to moderate breakouts

Acne · Core Formula

The Acne Solution^Rx

Adapalene · Clindamycin Phosphate · Niacinamide

Clearer, calmer breakouts.

$34.50/month

Starting with a 2-month supply

A prescription acne treatment built with three prescription-strength actives: adapalene to unclog pores, clindamycin to target the bacteria behind active breakouts, and niacinamide to keep your skin comfortable while they work, with centella asiatica and ceramides supporting your barrier throughout. It's a real prescription, designed for your skin and delivered to your door.

Treats the following acne concerns:

Free shipping
Skip or delay refills
HSA/FSA eligible
Ongoing support

Formulations

Active ingredients:

Adapalene: 0.3%
Clindamycin Phosphate 1%
Niacinamide: 2%

How & Why It Works

Speeds up skin cell turnover to clear clogged pores
Calms the bacteria behind active, inflamed breakouts
Helps reduce oiliness and keep pores looking clear
Fades the look of post-acne marks over time
Supports smoother, more even-looking texture
Supports the skin barrier so treatment stays comfortable
Compounded by a licensed pharmacy for each prescription

As with any prescription retinoid, some people notice mild, temporary effects as their skin adjusts to treatment, sometimes called “the purge.” These are typically short-lived and manageable with simple care steps.

Common adjustment effects can include mild dryness, peeling, or a temporary increase in breakouts, usually in the first 2 to 4 weeks. Applying a moisturizer helps ease irritation, and most people find their skin settles as the medication starts working. A board-certified dermatologist on our clinical team reviews your case and sets a formulation appropriate for your skin.

How to Use

After cleansing, apply a pea-sized amount to your fingertips and gently massage onto your face at night, or as directed by the board-certified dermatologist on your clinical team.

Follow with a gentle, hydrating moisturizer to keep your skin comfortable as it adjusts.

Wear a broad-spectrum sunscreen, minimum SPF 30, every morning. Prescription retinoids like adapalene can make your skin more sensitive to sun, so daily protection isn’t optional.

Most people see visible changes in 6–12 weeks with consistent nightly use
Each bottle is approximately a one-month supply

Pairs Well With

The Red Mark Solution

A prescription formula that helps fade the look of post-acne red marks and even out tone.

100% Compounded Online PharmacyPrescription-Only TreatmentsNo Long-Term Commitments

What's The Acne Solution?

Treats the following acne concerns:

Free shipping
Skip or delay refills
HSA/FSA eligible
Ongoing support

Formulations

Active ingredients:

Adapalene: 0.3%
Clindamycin Phosphate 1%
Niacinamide: 2%

How & Why It Works

Speeds up skin cell turnover to clear clogged pores
Calms the bacteria behind active, inflamed breakouts
Helps reduce oiliness and keep pores looking clear
Fades the look of post-acne marks over time
Supports smoother, more even-looking texture
Supports the skin barrier so treatment stays comfortable
Compounded by a licensed pharmacy for each prescription

How to Use

After cleansing, apply a pea-sized amount to your fingertips and gently massage onto your face at night, or as directed by the board-certified dermatologist on your clinical team.

Follow with a gentle, hydrating moisturizer to keep your skin comfortable as it adjusts.

Wear a broad-spectrum sunscreen, minimum SPF 30, every morning. Prescription retinoids like adapalene can make your skin more sensitive to sun, so daily protection isn’t optional.

Most people see visible changes in 6–12 weeks with consistent nightly use
Each bottle is approximately a one-month supply

Pairs Well With

The Red Mark Solution

A prescription formula that helps fade the look of post-acne red marks and even out tone.

What our customers are saying.

Maya's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“I finally stopped getting a new breakout every few days”

“My acne wasn't severe, but it was incredibly persistent. As soon as one spot started clearing, another one would show up around my chin or cheeks. I had tried so many over-the-counter products that my routine had become ridiculous. I started the Acne Solution and the first few weeks were mostly about letting my skin adjust. Around the second month, I realized I wasn't constantly dealing with new breakouts anymore. I'm a little over three months in now and my skin is so much calmer and more predictable.”

Maya, 27 · Verified Buyer

Jordan's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“My clogged pores are finally under control”

“My biggest issue was congestion rather than huge pimples. My forehead and cheeks were covered in tiny bumps and clogged pores that never completely went away. Makeup made the texture even more obvious. After about three months with DermClick, my forehead looks noticeably smoother and I have far fewer clogged areas around my cheeks and nose. I still get an occasional spot, but nothing like before.”

Jordan, 31 · Verified Buyer

Nisha's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“One prescription replaced half my routine”

“I had been buying separate products for breakouts, clogged pores, oiliness and the marks left behind afterward. My bathroom looked like a skincare store and somehow my skin was still breaking out. I wanted something simpler. I've been using the Acne Solution consistently for about three months and the biggest difference is how much calmer my skin is. I have fewer active breakouts, the little bumps along my jaw have improved, and some of the newer marks are already starting to look lighter.”

Nisha, 34 · Verified Buyer

Chloe's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“The chin breakouts that kept coming back finally slowed down”

“For almost a year I kept getting the same group of pimples around my chin and lower cheeks. They weren't severe enough that I thought I needed anything aggressive, but they never really stopped. After around ten weeks with the Acne Solution, I could finally see a pattern changing. I was getting fewer new spots and the ones I did get seemed smaller and easier to deal with. At three months, the difference between my before photos and now is very noticeable.”

Chloe, 24 · Verified Buyer

Jasmine's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“My skin looks calmer even without makeup”

“I have oily, acne-prone skin and was constantly dealing with small breakouts across my forehead and cheeks. What bothered me almost as much as the pimples was that my skin always looked irritated and uneven. I started DermClick a little over three months ago. The first couple of weeks weren't dramatic, but gradually I noticed fewer new breakouts and less congestion. Now my skin looks calmer and smoother, and I don't feel like I need foundation just to make everything look even.”

Jasmine, 29 · Verified Buyer

Emily's acne before and after using The Acne Solution

BeforeAfter

No makeup, no touchups

★★★★★

“Apparently adult acne really is a thing”

“I thought breakouts were something I'd leave behind in my twenties, but in my mid-30s I started getting recurring spots around my jaw and lower cheeks. Nothing was terrible individually, but there was almost always something healing or something new appearing. After about twelve weeks on the Acne Solution, my skin is much more consistent. I'm getting fewer breakouts, my pores look less congested, and the newer marks from old spots are fading. It's the first routine in a long time that I've actually wanted to stick with.”

Emily, 36 · Verified Buyer

The clinical team

The medicine behind your prescription is built by the doctors you already follow.

The Acne Solution^Rx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu — three board-certified dermatologists with decades of combined experience treating real patients. Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.

Dr. Lindsey Zubritsky MDDr. Mamina Turegano, MDDr. Jenny Liu, MD

What's in the bottle

Real actives. Named, not hidden.

The Acne Solution^Rx pairs three prescription actives with two supporting ingredients designed to keep your barrier comfortable while the medication does its work.

Active Ingredients

Adapalene

THE CORRECTOR

A prescription-strength retinoid. Unclogs pores, supports clearer texture, and helps calm the breakouts forming under the surface before you see them.

Clindamycin Phosphate

THE TARGETED ANTIBIOTIC

A topical antibiotic that calms the bacteria driving active, inflamed breakouts — working on what's already on your skin while adapalene works on what's coming.

Niacinamide

THE BUFFER

A form of vitamin B3 that helps reduce redness, supports your skin barrier, and makes prescription actives more tolerable. Irritation is the top reason people quit retinoids — this is the reason you won't.

Supporting Ingredients

Centella Asiatica

THE CALMER

A clinically studied botanical that soothes irritation and supports recovery. The quiet ingredient that keeps the strong ones comfortable.

Ceramides

THE BARRIER REPAIR

Lipids that reinforce the skin barrier and lock in moisture. Barrier health is what lets you stay on treatment — ceramides protect the foundation.

Exact concentrations are determined by your dermatology provider based on your assessment, your tolerance, and your skin's history. Compounded medications are not FDA-approved.

What to expect

A nightly reset for clearer-looking skin.

Applying acne treatment to acne-prone skin

The Acne Solution^Rx works while you sleep. Prescription-strength adapalene unclogs pores, clindamycin phosphate calms the bacteria behind active breakouts, and niacinamide keeps your barrier comfortable through the process.

Helps clear active breakouts
Unclogs pores and reduces oiliness
Fades post-acne marks over time
Supports clearer, more even skin texture
Gentle enough for first-time prescription users

Your best skin starts here.

The Acne Solution^Rx is a Core-tier prescription. That means it's strong enough to actually move the needle on breakouts you've been trying to clear on your own — and gentle enough to be your first prescription, not your last resort.

Ideal for you if you're

Dealing with mild to moderate acne — breakouts that come back no matter what you swap into your routine.
Tired of stacking OTC products that promise prescription-strength results without the prescription.
Noticing clogged pores, oiliness, or post-acne marks alongside the breakouts themselves.
Ready for your first prescription — or stepping up from over-the-counter retinoids like adapalene 0.1% (Differin) that have stopped working.
Able to tolerate a prescription retinoid, as confirmed during your assessment.

Consider a different fit if you're:

Dealing with severe acne-prone skin or deep breakouts that are leaving lasting marks — The Advanced Acne Solutionᴿˣ is built for higher-intensity cases.
Pregnant, nursing, or trying to conceive — many of our actives aren't appropriate; your assessment will route you to a safer option.
Primarily concerned about fine lines or signs of aging — The Anti-Aging Solution is built for that.
Mostly dealing with persistent redness or rosacea flushing — The Redness Control Formula is built for that.
Already on isotretinoin (Accutane), or finished a course within the past 6 months — we'll need to space your treatment appropriately.

Realistic timeline

What you may see in 6–12 weeks.

Prescription acne treatment isn't a one-week fix. Real results take time — but they're real, and they hold.
Here's what most people experience:

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

Smiling woman touching her neck after a skincare routine

Weeks 1–2

Adjustment

Your skin gets used to the prescription. You may notice mild dryness, peeling, or a temporary increase in breakouts as clogged pores work their way to the surface. This is the medication doing its job.

Weeks 3–6

Calming

Active breakouts may start to slow. Visible irritation looks calmer. Your skin's texture begins to even out. This is the point most people feel the shift.

Weeks 7–12

Visible clearing

Fewer new breakouts. Pores look smaller. Post-acne marks begin to fade. Your skin starts to look like a calmer version of itself.

Beyond 12 weeks

Maintenance and adjustment

Your DermClick care team checks in. If your skin has plateaued or needs more support, your formula is adjusted. This is where most acne treatments fall apart — and where we're built differently.

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

How DermClick works

Three steps. No appointments. Reviewed by a board-certified dermatologist within one business day.

Tell us about your skin.

Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.

Close-up of uneven tone and pigmentation

One business day review

Your case is reviewed within one business day, and your prescription is written by a board-certified dermatologist on our clinical team.

DermClick dermatologist reviewing a formula on a laptop

Adapalene

Clindamycin Phosphate

Niacinamide

Hydroquinone

Your prescription arrives

Your formula is compounded by a licensed pharmacy and shipped to your door — usually within a week. Your DermClick care team stays with you, adjusting your formula as your skin responds.

DermClick prescription bottle and box inside a delivery package

See the full process →

Frequently Asked Questions

Should I start with The Acne Solutionᴿˣ or step up to The Advanced Acne Solutionᴿˣ?

The Acne Solutionᴿˣ is our Core-tier formula for mild to moderate acne-prone skin and for people who haven't been on a prescription retinoid before. The Advanced Acne Solutionᴿˣ is the Advanced tier — higher-intensity actives, formulated for stubborn acne-prone skin with deep or recurring breakouts that haven't responded to over-the-counter or first-line prescription care. If you're not sure, take the assessment. A board-certified dermatologist on your care team will tell you which one matches where your skin actually is — not where you think it should be.

Will I get "the purge" with this?

Possibly, in the first 2 to 4 weeks. Adapalene accelerates cell turnover, which can push clogged material to the surface before it clears. This isn't the prescription making things worse — it's the prescription doing its job. Most people get through the adjustment period and come out the other side with clearer skin. The niacinamide and Centella asiatica in the formula are included specifically to keep this phase manageable.

Can I use this with my current skincare routine, or do I have to start over?

Most of your routine can stay. Gentle cleansers, fragrance-free moisturizers, and broad-spectrum SPF all pair well with The Acne Solutionᴿˣ. What you should pause: other topical retinoids (additional adapalene, tretinoin, tazarotene, retinol), high-concentration acids (salicylic, glycolic, lactic), and benzoyl peroxide — which can deactivate adapalene when layered directly. A board-certified dermatologist on your care team will review your current products during your assessment and tell you exactly what to keep, drop, and add.

Is The Acne Solutionᴿˣ safe with pregnancy, nursing, or other medications?

The assessment specifically asks. Many of our actives aren't appropriate during pregnancy or nursing — if any of these apply to you, a board-certified dermatologist on your care team will route you to a safer alternative. If we can't safely prescribe for you, we'll tell you before charging you. We don't write prescriptions that shouldn't be written.

When will I see results?

Most people start noticing a real shift between weeks 4 and 8 with consistent nightly use. Weeks 1–2 are the adjustment period. Weeks 3–6, breakouts may start to slow and visible irritation can look calmer. Weeks 6–12, fewer new breakouts, smaller-looking pores, and post-acne marks begin to fade. Acne-prone skin care is steady, not dramatic — but the results can hold.

What type of skin is The Acne Solutionᴿˣ designed for?

It's designed for mild to moderate acne-prone skin — particularly skin that breaks out consistently regardless of routine changes, shows clogged pores and oiliness alongside active breakouts, or has tried OTC retinoids like adapalene 0.1% (Differin) without getting the results a prescription concentration delivers. It's gentle enough for sensitive skin and designed for daily use without the harshness that comes with stronger acne formulas.

Where can I find full safety information?

Full prescribing details, including side effects, drug interactions, and who shouldn't use this treatment, are available on our Important Safety Information page. We recommend reading it before starting treatment.

The Acne Solution^Rx is our Core-tier acne treatment, built for mild to moderate breakouts. If your skin needs more — or less — there's a tier built for that. Your assessment routes you to the one that fits.

Core