Acne · Core

The Acne
SolutionRx

A Simpler Step for Clearer, Healthier Skin.

30-day supplyHSA/FSA eligibleFree shipping

Acne · Core

The Acne SolutionRx

A Simpler Step for Clearer, Healthier Skin.

30-day supplyHSA/FSA eligibleFree shipping

Designed to clear stubborn breakouts — without the wait or the price tag of an in-office visit.

Built with prescription-strength adapalene to unclog pores, clindamycin to target acne bacteria, and niacinamide to keep your skin barrier calm. A real prescription, designed for your skin, delivered to your door.

Read important safety information →

Common concerns:

Acne-prone skinClogged-looking poresUneven textureOilinessPost-acne marks

Designed by board-certified dermatologists. Prescribed by a board-certified dermatologist on our clinical team.

all-in, no surprises

$79/mo

Cancel anytime. Skip or delay refills.

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Short assessment · Reviewed within 24 hours

100% Compounded Online PharmacyPrescription-Only TreatmentsNo Long-Term Commitments

The clinical team

The medicine behind your prescription is built by the doctors you already follow.

The Acne SolutionRx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu — three board-certified dermatologists with combined decades of clinical experience treating real patients. Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.

DermClick founding dermatologists
Dr. Lindsey Zubritsky MDDr. Mamina Turegano, MDDr. Jenny Liu, MD

Your best skin starts here.

The Acne SolutionRx is a Core-tier prescription. That means it's strong enough to actually move the needle on breakouts you've been trying to clear on your own — and gentle enough to be your first prescription, not your last resort.

Ideal for you if you're

  • Dealing with mild to moderate acne — breakouts that come back no matter what you swap into your routine

  • Tired of stacking OTC products that promise prescription-strength results without the prescription

  • Noticing clogged pores, oiliness, or post-acne marks alongside the breakouts themselves

  • Ready for your first prescription — or stepping up from over-the-counter retinoids like adapalene 0.1% (Differin) that have stopped working

  • Able to tolerate a prescription retinoid, as confirmed during your assessment

Consider a different fit if you're:

  • Dealing with severe acne-prone skin or deep breakouts that are leaving lasting marks — The Acne Solution Advanceᴿˣ is built for higher-intensity cases

  • Pregnant, nursing, or trying to conceive —many of our actives aren't appropriate; your assessment will route you to a safer option

  • Primarily concerned about fine lines or signs of agingThe Anti-Aging Solution is built for that

  • Mostly dealing with persistent redness or rosacea flushing — The Acne & Anti-Aging Formula is built for that

  • Already on isotretinoin (Accutane),or finished a course within the past 6 months — we'll need to space your treatment appropriately

What to expect

A nightly reset for clearer-looking skin.

Applying acne treatment to acne-prone skin

The Acne SolutionRx works while you sleep. Prescription-strength adapalene unclogs pores, clindamycin phosphate calms the bacteria behind active breakouts, and niacinamide keeps your barrier comfortable through the process.

  • Helps clear active breakouts
  • Unclogs pores and reduces oiliness
  • Fades post-acne marks over time
  • Supports clearer, more even skin texture
  • Gentle enough for first-time prescription users
Applying acne treatment to acne-prone skin

Results you can see. Confidence you can feel!

Realistic timeline

What you may see in 6–12 weeks.

Prescription acne treatment isn't a one-week fix. Real results take time — but they're real, and they hold.
Here's what most people experience:

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

Smiling woman touching her neck after a skincare routine
1

Weeks 1–2

Adjustment

Your skin gets used to the prescription. You may notice mild dryness, peeling, or a temporary increase in breakouts as clogged pores work their way to the surface. This is the medication doing its job.
2

Weeks 3–6

Calming

Active breakouts may start to slow. Visible irritation looks calmer. Your skin's texture begins to even out. This is the point most people feel the shift.
3

Weeks 6–12

Visible clearing

Fewer new breakouts. Pores look smaller. Post-acne marks begin to fade. Your skin starts to look like a calmer version of itself.
4

Beyond 12 weeks

Maintenance and adjustment

Your DermClick care team checks in. If your skin has plateaued or needs more support, your formula is adjusted. This is where most acne treatments fall apart — and where we're built differently.

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

What's in the bottle

Real actives. Named, not hidden.

The Acne SolutionRx pairs two prescription actives with two supporting ingredients designed to keep your barrier comfortable while the medication does its work.

Active Ingredients

Inactive Ingredients

Exact concentrations are determined by your dermatology provider based on your assessment, your tolerance, and your skin's history. Compounded medications are not FDA-approved.

How DermClick works

Three steps. No appointments. Reviewed by a board-certified dermatologist within 24 hours.

Tell us about your skin.

Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.

Close-up of acne-prone skin
Close-up of skin texture and fine lines
Close-up of breakout redness
Close-up of uneven tone and pigmentation

24-hour review

Your case is reviewed within 24 hours, and your prescription is written by a board-certified dermatologist on our clinical team.

DermClick dermatologist reviewing a formula on a laptop
Adapalene
Clindamycin Phosphate
Niacinamide
Hydroquinone

Your prescription arrives

Your formula is compounded by a licensed pharmacy and shipped to your door — usually within a week. Your DermClick care team stays with you, adjusting your formula as your skin responds.

DermClick prescription bottle and box inside a delivery package
See the full process →

Frequently Asked Questions

Should I start with The Acne Solutionᴿˣ or step up to The Advanced Acne Solutionᴿˣ?

The Acne Solutionᴿˣ is our Core-tier formula for mild to moderate acne-prone skin and for people who haven't been on a prescription retinoid before. The Advanced Acne Solutionᴿˣ is the Advanced tier — higher-intensity actives, formulated for stubborn acne-prone skin with deep or recurring breakouts that haven't responded to over-the-counter or first-line prescription care. If you're not sure, take the assessment. A board-certified dermatologist on your care team will tell you which one matches where your skin actually is — not where you think it should be.

Will I get "the purge" with this?

Possibly, in the first 2 to 4 weeks. Adapalene accelerates cell turnover, which can push clogged material to the surface before it clears. This isn't the prescription making things worse — it's the prescription doing its job. Most people get through the adjustment period and come out the other side with clearer skin. The niacinamide and Centella asiatica in the formula are included specifically to keep this phase manageable.

Can I use this with my current skincare routine, or do I have to start over?

Most of your routine can stay. Gentle cleansers, fragrance-free moisturizers, and broad-spectrum SPF all pair well with The Acne Solutionᴿˣ. What you should pause: other topical retinoids (additional adapalene, tretinoin, tazarotene, retinol), high-concentration acids (salicylic, glycolic, lactic), and benzoyl peroxide — which can deactivate adapalene when layered directly. A board-certified dermatologist on your care team will review your current products during your assessment and tell you exactly what to keep, drop, and add.

Is The Acne Solutionᴿˣ safe with pregnancy, nursing, or other medications?

The assessment specifically asks. Many of our actives aren't appropriate during pregnancy or nursing — if any of these apply to you, a board-certified dermatologist on your care team will route you to a safer alternative. If we can't safely prescribe for you, we'll tell you before charging you. We don't write prescriptions that shouldn't be written.

When will I see results?

Most people start noticing a real shift between weeks 4 and 8 with consistent nightly use. Weeks 1–2 are the adjustment period. Weeks 3–6, breakouts may start to slow and visible irritation can look calmer. Weeks 6–12, fewer new breakouts, smaller-looking pores, and post-acne marks begin to fade. Acne-prone skin care is steady, not dramatic — but the results can hold.

What type of skin is The Acne Solutionᴿˣ designed for?

It's designed for mild to moderate acne-prone skin — particularly skin that breaks out consistently regardless of routine changes, shows clogged pores and oiliness alongside active breakouts, or has tried OTC retinoids like adapalene 0.1% (Differin) without getting the results a prescription concentration delivers. It's gentle enough for sensitive skin and designed for daily use without the harshness that comes with stronger acne formulas.

The Acne SolutionRx is our Core-tier acne treatment, built for mild to moderate breakouts. If your skin needs more — or less — there's a tier built for that. Your assessment routes you to the one that fits.