Anti-aging · Advanced

The Advanced Anti-Aging Solution Rx

Your "Level Up" for Deeper, Maximum-Strength Renewal.

30-day supplyHSA/FSA eligibleFree shipping

Anti-aging · Advanced

The Advanced Anti-Aging Solution Rx

Your "Level Up" for Deeper, Maximum-Strength Renewal.

30-day supplyHSA/FSA eligibleFree shipping

When tretinoin alone isn't enough — deeper wrinkles, loss of firmness, visible photoaging — this is the prescription your skin has been waiting for.

Built with tazarotene and niacinamide — two prescription actives working together for texture, tone, and firmness support — plus Centella asiatica to soothe the adjustment period and ceramides to reinforce the barrier through maximum-strength treatment.

Read important safety information →

Common concerns:

Deeper wrinklesSkin textureLoss of firmnessPhotoagingUneven tone

✓ Designed by board-certified dermatologists. Prescribed by a board-certified dermatologist on our clinical team.

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Short assessment · Reviewed within 24 hours

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The clinical team

The medicine behind your prescription is built by the doctors you already follow.

The Advanced Anti-Aging Solution Rx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu — three board-certified dermatologists with combined decades of clinical experience treating patients at every stage of aging.

Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.

DermClick founding dermatologists
Dr. Lindsey Zubritsky MDDr. Mamina Turegano, MDDr. Jenny Liu, MD

Built for skin that's past the fine-line stage.

Deeper wrinkles, visible photoaging, loss of firmness that first-line retinoids haven't touched.

The Advanced Anti-Aging Solution Rx is our maximum-strength prescription anti-aging formula. Tazarotene and niacinamide work together as co-actives — supporting texture, tone, and firmness — while Centella asiatica and ceramides keep your barrier intact through the more intense adjustment period.

Ideal for you if you're

  • Dealing with deeper wrinkles, loss of firmness, or visible photoaging

  • You've been on prescription tretinoin and plateaued, or stopped seeing results

  • Watching texture changes, sun damage, or sagging develop alongside the lines

  • Looking for stronger results than first-line prescription anti-aging can deliver

  • Familiar with prescription retinoids and able to tolerate a maximum-strength formulation, as confirmed during your assessment

Consider a different fit if you're:

  • New to prescription retinoidsThe Anti-Aging SolutionRx (Core) is the better starting point and steps up cleanly if needed

  • Pregnant, nursing, or trying to conceive — tazarotene is FDA Pregnancy Category X and is contraindicated; your assessment will route you to a safer option

  • Currently fighting active breakouts alongside agingThe Advanced Acne FormulaRx is built for that

  • Primarily dealing with melasma or persistent pigmentationThe Brightening SolutionRx is built for that

  • Already on isotretinoin (Accutane), or finished a course within the past 6 months — we'll need to space your treatment appropriately

What to expect

One nightly step. Maximum-strength renewal.

Woman applying anti-aging cream to her face

The Advanced Anti-Aging Solution Rx works while you sleep. Tazarotene is selected when stronger retinoid support is appropriate for deeper lines, visible photoaging, and firmness concerns. Niacinamide evens tone, Centella asiatica soothes the higher-intensity adjustment, and ceramides reinforce your barrier so you can stay on the formula long enough to see results.

  • Smooths deeper wrinkles and visible photoaging
  • Improves firmness, texture, and skin clarity
  • Supports maximum-strength retinoid activity
  • Builds collagen and addresses sun damage over time
Woman applying anti-aging cream to her face

Realistic timeline

What you may see in 6–12 weeks.

Maximum-strength prescription anti-aging isn't a one-week fix — and the concerns you're addressing took years to develop. Real results take time. They also hold. Here's what most people experience.

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

Smiling woman touching her neck after a skincare routine
1

Weeks 1–2

Adjustment

Your skin gets used to the prescription. Moderate dryness, peeling, or temporary sensitivity is common. With tazarotene-strength actives, the adjustment can feel sharper than first-line tretinoin. This is the medication doing its job.
2

Weeks 3–6

Calming

The adjustment settles. Your skin texture starts to feel smoother. Tone begins to look more uniform. This is the point most people feel the shift.
3

Weeks 6–12

Visible smoothing and firming

Deeper lines look softer. Photoaging looks less pronounced. Skin starts to look firmer and more renewed. The kind of result first-line retinoids plateau before delivering.
4

Beyond 12 weeks

Maintenance and collagen building

Tazarotene's long-term work — collagen building, sustained smoothness, sustained firmness — compounds over months and years. Your dermatology care team checks in and adjusts your formula as your skin evolves.

Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.

What's in the bottle

Real actives. Named, not hidden.

The Advanced Anti-Aging Solution Rx pairs one maximum-strength prescription retinoid with three supporting ingredients designed to keep your barrier comfortable through higher-intensity treatment. Four ingredients. One purpose.

Active Ingredients

Inactive Ingredients

Exact concentrations are determined by a board-certified dermatologist on your care team based on your assessment, your tolerance, and your skin's history. Compounded medications are not FDA-approved.

How DermClick works

Three steps. No appointments. Reviewed by a board-certified dermatologist within 24 hours.

Tell us about your skin.

Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.

Close-up of acne-prone skin
Close-up of skin texture and fine lines
Close-up of breakout redness
Close-up of uneven tone and pigmentation

24-hour review

Your case is reviewed within 24 hours, and your prescription is written by a board-certified dermatologist on our clinical team.

DermClick dermatologist reviewing a formula on a laptop
Tazarotene
Niacinamide

Your prescription arrives

Your formula is compounded by a licensed pharmacy and shipped to your door — usually within a week. Your dermatologist stays with you, adjusting your formula as your skin responds.

DermClick prescription bottle and box inside a delivery package
See the full process →

Frequently Asked Questions

Should I start with The Anti-Aging Solutionᴿˣ or step up to the Advanced version?

The Anti-Aging Solutionᴿˣ is our first-line prescription formula — built around tretinoin, ideal for fine lines, early texture changes, and dullness. The Advanced Anti-Aging Solutionᴿˣ is the maximum-strength tier — built around tazarotene, a next-generation retinoid stronger than tretinoin, formulated for deeper wrinkles, loss of firmness, and visible photoaging that hasn't responded to first-line treatment. If you're not sure, take the assessment. A board-certified dermatologist on your care team will tell you which one matches where your skin actually is — not where you think it should be.

How is tazarotene different from tretinoin?

Tazarotene is a next-generation prescription retinoid that's typically more potent than tretinoin and is used when deeper texture, tone, and firmness concerns need stronger support. That power comes with a sharper adjustment period: more dryness, more peeling, more sensitivity, especially in the first 4 to 8 weeks. That's why the Advanced formula includes ceramides and Centella asiatica for barrier support — they make tazarotene livable. If your skin has plateaued on tretinoin, this is typically the next step.

Will I 'purge' on tazarotene if I don't have acne?

If you don't have active breakouts, you typically won't experience a breakout-style purge. What you may experience instead is a more pronounced adjustment period than with first-line tretinoin: moderate dryness, peeling, or sensitivity for 2 to 8 weeks as your skin acclimates to the higher-strength active. The ceramides and Centella asiatica in the formula are included specifically to keep this phase manageable. If it gets uncomfortable, message us and we'll adjust your ramp-up or your formula.

Can I use this with my current skincare routine, or do I have to start over?

Most of your routine can stay. Gentle cleansers, hydrating serums, broad-spectrum SPF (non-negotiable on tazarotene), and barrier-supporting moisturizers all pair well with The Advanced Anti-Aging Solutionᴿˣ. What you should pause: other topical retinoids (tretinoin, adapalene, additional tazarotene, retinol), strong exfoliants like glycolic acid or salicylic acid at high concentrations, vitamin C serums at night (use them in the morning instead), and physical scrubs. A board-certified dermatologist on your care team will review your current products during your assessment and tell you exactly what to keep, what to drop, and what to add.

Is The Advanced Anti-Aging Solutionᴿˣ safe with pregnancy, nursing, or other medications?

The assessment specifically asks. The Advanced Anti-Aging Solutionᴿˣ contains tazarotene, which is FDA Pregnancy Category X — it is contraindicated during pregnancy due to risk of birth defects, and effective contraception is required during treatment for anyone who could become pregnant. It is also not recommended while nursing. If any of these apply to you, a board-certified dermatologist on your care team will route you to a safer alternative. If we can't safely prescribe for you, we'll tell you before charging you. We don't write prescriptions that shouldn't be written.

When will I see results?

Most people start noticing a real shift between weeks 8 and 12 with consistent nightly use. Here's roughly what to expect: weeks 1–2 are the adjustment period. Weeks 3–6, your texture starts to smooth and your tone begins to even out. Weeks 6–12, deeper lines look softer and your skin looks firmer. Beyond 12 weeks, the collagen-building and sun-damage-correcting work compounds over months and years. Maximum-strength treatment is steady, not dramatic — but the results hold, and they're the strongest thing in topical anti-aging short of in-office procedures.

The Advanced Anti-Aging Solution Rx is our maximum-strength anti-aging formula — built for deeper lines, visible photoaging, and skin that's plateaued on first-line treatment. If you're earlier in your anti-aging journey, The Anti-Aging SolutionRxis the starting point, with a clear step-up path when you're ready. And if sun damage and uneven tone are part of your picture alongside the lines, The Brightening SolutionRxis built to pair with it. Your assessment routes you to what fits — and tells you what works together.