Important Safety Information

The Anti-Aging Solution^Rx

Please read this information carefully before using your prescription. Keep it for reference, and message your DermClick care team if you have any questions.

What it is

The Anti-Aging Solution^Rx is a compounded prescription topical medication, formulated by a licensed compounding pharmacy for individual patients under the direction of a licensed dermatology provider, working from protocols built by DermClick's founding board-certified dermatologists.

Active ingredients

Tretinoin - a prescription-strength retinoidNiacinamide - a barrier-supporting vitamin B3 derivative

Inactive ingredients

Centella asiatica - a soothing botanical ingredientCeramides - barrier-reinforcing lipids

What it treats

The Anti-Aging Solution^Rx is prescribed for the treatment of fine lines and early signs of aging, including:

Fine lines and early wrinkles
Uneven skin texture
Dullness and uneven tone
Early signs of photoaging
Loss of overall skin clarity

Your dermatology provider has determined this formulation is appropriate for your specific skin based on the assessment you completed.

Who should not use it

Do not use The Anti-Aging Solution^Rx if any of the following apply to you. If your situation changes after your assessment, contact your DermClick care team before continuing use.

You are pregnant, may be pregnant, or are trying to conceive
You are breastfeeding
You have a known allergy or sensitivity to tretinoin, niacinamide, Centella asiatica, ceramides, or any other listed ingredient
You have used oral isotretinoin, commonly known as Accutane, within the past 6 months
You have eczema or a severely compromised skin barrier on the application area
You have an active skin infection or open wounds in the application area
You are under 12 years of age

Warnings and precautions

Sun sensitivity

Tretinoin makes your skin more sensitive to sunlight, and sun exposure is the single fastest way to undo progress on fine lines and photoaging. Apply broad-spectrum SPF 30 or higher every morning, and avoid prolonged sun exposure, tanning beds, and sun lamps. Daily SPF is non-negotiable during treatment.

Pregnancy and nursing

Tretinoin is contraindicated during pregnancy and not recommended while breastfeeding. If any of these become true during your treatment, stop using the medication immediately and contact your DermClick care team.

Eye, lip, and nostril contact

Avoid contact with eyes, lips, the corners of the nose, and any mucous membranes. If contact occurs, rinse thoroughly with cool water.

Waxing and laser treatments

Do not wax, undergo laser treatments, or use chemical peels on areas where you apply this medication. Pause use for at least one week before and after any such procedure, and consult your DermClick care team.

Drug interactions

Tell your dermatology provider about any prescription or over-the-counter medications you use, especially:

Other topical retinoids, including additional tretinoin, adapalene, tazarotene, or retinol
Benzoyl peroxide products, which can be used at separate times of day and can degrade tretinoin if layered
Salicylic acid or glycolic acid exfoliants at high concentrations
Vitamin C serums, which can be used in the morning but are not recommended layered at night
Hormonal medications

Possible side effects

Common side effects

These may happen especially in the first 2 to 6 weeks of treatment.

Mild dryness, flaking, or peeling
Temporary redness or mild irritation
Mild burning or stinging when first applied
Increased sensitivity to sun
Temporary sensitivity to skincare products you previously tolerated

Less common side effects

Significant or persistent redness, swelling, or itching
Severe peeling or barrier disruption
Worsening or persistent burning sensation
Skin discoloration

These are typical of prescription retinoid treatment and usually settle within the first 4 to 6 weeks as your skin adjusts. The ceramides and Centella asiatica in the formula are included specifically to manage this phase. Your DermClick care team can adjust your application frequency or your formula if these symptoms become uncomfortable.

Rare but serious

Contact your DermClick care team or seek emergency care if you experience:

Severe rash, hives, or swelling of the face, lips, tongue, or throat
Difficulty breathing
Signs of severe allergic reaction
Severe blistering, crusting, or skin sloughing at the application site

How to use it

Application

Apply a thin layer to clean, dry skin on the affected area at night, after washing your face and patting it dry. Wait 20 to 30 minutes after washing before applying to reduce irritation, which matters with tretinoin.

Frequency

Start with every other night for the first 2 weeks. Increase to nightly as your skin tolerates it. Your DermClick care team will adjust your ramp-up plan based on how your skin responds.

Amount

A pea-sized amount is enough for the entire face. More is not better and will cause irritation without improving results.

Storage

Store at room temperature, away from direct sunlight and heat. Keep the cap closed when not in use. Do not freeze. Tretinoin degrades with light and air exposure, so store accordingly.

Shelf life

Use within the period indicated on your prescription label. Do not use after the expiration date.

Morning

Gentle cleanser, vitamin C serum (optional, supports anti-aging synergy), moisturizer, broad-spectrum SPF 30+

Evening

Gentle cleanser, then The Anti-Aging Solution^Rx, then a barrier-supporting moisturizer.

If you have a reaction

For mild irritation

Reduce application frequency to every third night, apply a barrier-supporting moisturizer 15 minutes after the medication, and message your DermClick care team. We can adjust your formula or your ramp-up plan.

For moderate to severe reactions

Stop using the medication. Message your DermClick care team. Send photos if you can so your dermatology provider can review and respond.

For medical emergencies

For severe rash, swelling of the face or throat, difficulty breathing, or signs of severe allergic reaction, call 911 or go to your nearest emergency room immediately.

Contact your DermClick care team

Phone: 1-833-496-4045
Email: support@dermclick.com
Account dashboard: message your care team directly at app.dermclick.com

Message your care team

About compounded medications

Compounded medications are prepared by a licensed compounding pharmacy for individual patients, based on a prescription written by a licensed dermatology provider. They are not individually evaluated or approved by the FDA.

The active ingredients in The Anti-Aging Solution^Rx- tretinoin, niacinamide, Centella asiatica, and ceramides - are well-established ingredients used in clinical dermatology. Compounding allows your dermatology provider to combine them into a single formulation tailored to your skin, rather than asking you to layer a prescription retinoid, a barrier serum, a soothing serum, and a ceramide cream on top of each other. The supporting ingredients aren't optional extras - they are what makes the retinoid sustainable.

Your prescription is compounded by a 503A licensed compounding pharmacy and shipped directly to you.