Apply The Acne Solution as directed by the dermatologist on your case. Your prescription will come with specific instructions on how much to apply, when to apply it, and how to ease into the routine — and these instructions are personalized based on your skin type, history, and tolerance.
A few practical points that apply to most acne prescriptions of this type:
- Start slowly. Most prescription topical retinoids are introduced gradually — for example, every other night for the first one to two weeks — to allow the skin to adjust before moving to nightly use. Follow the schedule the dermatologist on your case gives you.
- Apply to clean, dry skin. A non-foaming gentle cleanser is recommended; apply the prescription a few minutes after washing, once the skin is fully dry.
- Layer a barrier moisturizer. A simple ceramide-based or barrier-repair moisturizer applied after the prescription helps reduce irritation in the first weeks.
Daily SPF 30 or higher is non-negotiable. Prescription retinoids and other actives in compounded acne formulas can increase sun sensitivity. Daily broad-spectrum sunscreen is part of the protocol, not optional.
- Pause other actives. If you are currently using over-the-counter retinols, BHA/AHA exfoliants, benzoyl peroxide, or another prescription product, the dermatologist on your case will tell you which to pause and for how long. See the article "Can I keep using my Differin, BHA, or Curology while starting DermClick acne?" for details.
If you experience persistent irritation, message the team. The dermatologist on your case can adjust the strength, the frequency, or the specific combination in your formula.