Yes. Every DermClick formula is a prescription product. The actives most commonly included — tretinoin, hydroquinone, clindamycin, eflornithine, prescription-strength azelaic acid — are not available over the counter in the United States and require a prescription from a licensed clinician. The DermClick formulas are dispensed by 503A compounding pharmacies once your dermatologist signs the prescription.
'Prescription strength' is a meaningful clinical statement, not a marketing claim. It means the active concentration and the active itself are at a level only a prescriber can authorize for you, with the safety, efficacy, and side-effect profile to match. The strength prescribed for your case depends on your skin type, prior retinoid exposure, tolerance, and condition severity — that's why two patients with similar concerns may receive different formulas.